雄激素源性脱发的鉴别诊断-读书报告（4）

工作日每天早上7:30~8:00, 浙江省人民医院皮肤科的医生们就开始英文专著早读会。我们发布中英文报告，有兴趣的医生可以和我们一起学习。

在专业英语专有名词翻译中，难免会有些不规范用词的中文译文，欢迎广大读者批评指正。

Keywords: growth (anagen, 生长期), cessation (catagen，退行期), and rest (telogen，休止期) phases.

Differential diagnosis（鉴别诊断）

The most important differential diagnoses are diseases which present with

diffuse nonscarring alopeciaincluding telogen effluvium, alopecia areata, and

trichotillomania.

最重要的鉴别诊断是那些表现为弥漫性非瘢痕性脱发的疾病，包括休止期脱发、斑秃、和拔毛癖。

Although androgenetic alopecia may show increasednumbers of telogen

hairs, telogen effluvium is clinically morediffuse and there are no miniaturized

hair follicles. It is important, however, to notethat both diseases

may present simultaneously and that chronic telogeneffluvium may uncover

occult androgenetic alopecia.

虽然雄激素源性脱发可以出现静止期毛发数量增加，但临床上静止期脱发更加弥漫，并且没有毛囊的微小化。然而，值得注意的是的是这两个疾病可以同时发生，慢性静止期脱发可能会提示隐匿的雄激素源性脱发。

Alopecia areata may show miniaturized hairfollicles, particularly in

very chronic cases. Characteristically, however,there is a major increase in

the number of hair follicles in catagen, telogen,and anagen and usually a

sparse peribulbar lymphocytic infiltrate ispresent, sometimes accompanied

by eosinophils. Without adequate clinicalinformation, distinction may be

impossible.

斑秃可以出现一些微小化的毛囊，特别是在非常慢性病程的病例中。然而，特征性的主要表现是在退行期、静止期和生长期毛囊数目增加，并通常在毛球周围有少量的淋巴细胞浸润，有时伴随嗜酸性粒细胞浸润。在没有足够临床信息时，鉴别诊断通常是不可能的。

In trichotillomania there are increased numbersof hair follicles in catagen

and telogen but in addition there istrichomalacia (short, incompletely keratinized

hairs), pigmented casts, and distortion of hairshafts.

在拔毛癖中退行期和静止期毛囊数目增加，另外还有毛软化（短，没有完全角化的毛发），色素管型和毛干扭转。

（雄激素源性脱发文章完）

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本文译文：浙江省人民医院樊莎莎医师   2017-11-10